Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymus
نویسندگان
چکیده
منابع مشابه
A cell-intrinsic role for Mst1 in regulating thymocyte egress.
The MST1 kinase was recently identified as playing an essential role in the promotion of lymphocyte polarization and adhesion stimulated by chemokines and TCR signaling. However, the physiological relevance of the Mst1 pathway in thymocyte development is not completely understood. In this study, we analyzed the effect of Mst1 disruption on thymocyte development and migration. Mst1-deficient (Ms...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2012
ISSN: 2041-1723
DOI: 10.1038/ncomms2105